Clinical trial setup performance and research activity across the Shelford Group
The 150-day target: The government's Life Sciences Sector Plan commits to reducing clinical trial setup time to under 150 days by March 2026 — from regulatory submission to first participant recruited. The 150-day clock comprises three stages: MHRA/HRA approval (target: 60 days), site opening after approval (target: 60 days), and first participant recruited after site opening (target: 30 days). The data below relates to the site-level component: whether studies recruited their first participant within 90 days of HRA approval. This is a key NIHR Research Delivery Network performance metric, with funding implications for trusts.
Trial Setup Summary – Shelford Group
Source: NIHR Open Data Platform. Latest period: 12 months to February 2026. Previous period: 12 months to December 2025.
Total Studies Recruiting (Latest)
175
Across all 10 trusts, 12 months to Feb 2026
First Participant Within 90 Days
76
43.4% of studies met the benchmark
Shelford 90-Day Achievement Rate
43.4%
Up from 30.3% previous period · NIHR target: 80%
Trust-Level Trial Setup Performance
Source: NIHR Open Data Platform, 12 months to February 2026. Change column shows percentage point difference from previous period (12 months to December 2025).
Trust
Total Studies
Within 90 Days
After 90 Days
% Within 90d
Median Days
Change (pp)
First Participant Recruited Within 90 Days (% to Target)
Source: NIHR Open Data Platform. Latest: 12 months to February 2026. Previous: 12 months to December 2025. NIHR target is 80%.
Study Volume and Setup Performance by Trust
Source: NIHR Open Data Platform, 12 months to February 2026.
Source: Shelford Group data collection, 12 months to December 2025. Each bar shows the split between studies that recruited within 90 days (teal) and those that took longer (grey).
Future Additions
Planned data for future updates
This page will be expanded as additional research performance data becomes available. Potential additions include:
NIHR RDN recruitment data — commercial and non-commercial trial participant numbers by trust (published monthly by NIHR)
Commercial trial income — revenue from industry-sponsored trials (from trust annual reports, available July)
Recruitment to time and target — proportion of commercial trials meeting agreed recruitment targets
Trial portfolio size — number of active studies per trust on the NIHR portfolio
Setup time trends — quarterly tracking of 90-day performance against the March 2026 target